I rarely visit the Twitter website directly, the majority of my interaction is via Tweetdeck or various clients on my iPhone. Tweetdeck is fantastic, it even lets me view and post to various Facebook features like activity streams and photos and even Myspace.
Tweetdeck may very well be the first mainstream desktop client we all use to manage our social lives. Which gets me thinking about subscribing to multiple dating sites and having a Tweetdeck-like app to deal with all of the email, notes on members, etc, but that is for another post.
